Multiple studies in Cuba found that 5–10 mg of a sugar-derived form of policosanol, taken daily in the evening, can significantly reduce harmful cholesterol. Higher doses should be split in two, with one being taken with a meal earlier in the day.
An ancient Ayurvedic remedy made from the sap of a myrrh tree native to India, guggul has effectively lowered cholesterol in most published studies since the 1980s. It helps eliminate cholesterol, rather than blocking its production in the liver as statins do. Product formulations vary, so follow label directions or advice from a health practitioner.
During the past 30 years, at least 13 studies have looked at Pantesin, a patented form of vitamin B5 (pantethine), in lab, animal, and human trials. In one study, published in Vascular Health and Risk Management, harmful LDL cholesterol dropped by 11 percent among those taking 600 mg of Pantesin daily, for four weeks. It may enhance blood flow and favorably alter gut bacteria and cholesterol metabolism.
Sytrinol is a patented supplement ingredient derived from citrus and palm fruit. Research shows that in a month, 300 mg daily can lower total cholesterol by up to 30 percent, harmful LDL cholesterol by 27 percent, and triglycerides by 34 percent.