The Dark Side of Propylene Glycol: Side Effects And How to Avoid Them | HoneyColony
A 2014 National Center for Biotechnology Information (NCBI) report concludes that based on 44 articles, the propylene glycol used in e-cigarettes “produce mouth and throat irritation and dry cough.”
Additional Side Effects
Despite the FDA’s milquetoast evaluation of propylene glycol, there are several other health concerns, including:
Infants And Pregnant Women — Propylene glycol enters the body as an alcohol and metabolizes in the body’s enzyme pathways. These pathways do not mature in humans until 12 to 30 months of age. Infants and children below the age of 4 years, pregnant women, and those with kidney dysfunction or in renal failure are not able to eliminate propylene glycol in the body. Even the FDA concedes this inability to process and eliminate this product causes potential adverse reactions in infants and pregnant women as well as those with kidney problems. The World Health Organization (WHO) has specified that the acceptable daily intake of propylene glycol as a food additive is no more than 25 mg per kilogram of weight per 24 hours.
Potentially Toxic To The Liver And Kidneys – Propylene glycol is used in many IV medications, including Lorazepam, an anxiety-reducing and seizure treatment medication. Like Xanax, Lorazepam belongs in the benzodiazepines family of drugs, known for their widespread abuse. This drug is often administered to patients with extensive burns as sedation during the healing process or to psychiatric patients. When given Lorazepam for an extended period of time in large doses, clinicians have discovered possible kidney issues in the form of increased creatinine levels in the blood. Generally, creatinine (a product of muscle breakdown and growth) remains in consistent levels in the bloodstream, according to Axe. “Excess creatinine is a sign that the kidney is unable to process compounds at a normal rate.” A 2007 study from the University of Connecticut assessed the treatment of propylene glycol toxicity and also noted it can be dangerous for those with liver problems.