8 Harmful Effects of Soybean Oil | Nutrition Advance
An animal study compared the impact of a diet high in soybean oil to high fructose and coconut oil diets. The mice fed large amounts of soybean oil had significantly more weight gain, diabetes, and insulin resistance. Additionally, the soybean oil diet upregulated cancer, inflammation and obesity-related genes (2).
Another animal study fed mice a high-fat diet of either soybean, olive oil, MCT oil, peanut oil, or tea oil. Following the study, body weight and body fat were significantly higher in the soybean oil group compared to all others. Also, the soybean oil group had visible fatty liver disease—the MCT, olive oil, and tea oil mice did not (4).
In a study comparing butter and soybean oil, fat oxidation increased in the group fed butter. In the soybean fed group, subjects showed an inability to oxidize fat while resting (5).