Focused ultrasound opens the blood–brain barrier – Physics World
Focused ultrasound from outside the body can safely and reversibly open the blood–brain barrier in patients with Alzheimer’s disease, researchers in Canada have shown for the first time. The technique could offer a way to bypass the barrier and deliver therapeutic compounds to the brain that can treat Alzheimer’s and other neurologic disorders.
The blood–brain barrier separates the brain’s blood vessels from brain tissue. It regulates what can and can’t enter the brain, protecting it from toxins and pathogens in the blood. But it also presents a problem for the treatment of neurological diseases, because it blocks therapeutic drugs.