The Antonine Plague laid the groundwork for the unraveling of the Roman Empire. It exposed their dependency on connected trade routes. It lowered their standards for military service, which would both impair their geographical control and decrease esteem for Rome’s leadership.
The continued tradition of undertrained, ill-equipped soldiers, political breakdown, pressing germanic tribes, and a second virus outbreak, would all be major factors in the downfall of the Roman Empire.
But the crushing of its military by this virus was the first shot across the bow.medium The Virus That Crushed the Roman Army – Publishous – Medium