GreenMedInfo.com has compiled 236 studies related to acetaminophen’s toxicity, and a European Journal of Hospital Pharmacy editorial concluded, “We have considerable evidence that as well as not being particularly effective, neither is it particularly safe.” Some of the health risks linked to acetaminophen use include:
Gastrointestinal adverse events, including gastroduodenal ulcers and upper gastrointestinal hemorrhage
Acute liver failure necessitating transplantation
Abnormal liver function
What’s more, acetaminophen has been shown to be ineffective for treating back pain, “practically ineffective” for arthritis and “in the least effective quartile of drugs” for treating postoperative pain. It’s also only modestly effective for migraines and tension-type headaches, while no evidence shows that it works to relieve pain related to cancer, menstrual cramps, rheumatoid arthritis or the neck.