COVID-19: What’s RNA research got to do with it? : NewsCenter

One of the reasons viruses are such a challenge is that they change and mutate in response to drugs.

Anderson has found that alternative therapeutics, such as the gene-editing technology CRISPR, may additionally “usher in a new approach to how we target and combat infectious diseases,” he says.

For the past few years, Anderson’s lab has developed tools and delivery systems that use the RNA-targeting CRISPR-Cas13 to treat human genetic diseases that affect muscle function. CRISPR-Cas13 is like a molecular pair of scissors that can target specific RNAs for degradation, using small, programmable guide RNAs.

rochester.edu COVID-19: What’s RNA research got to do with it? : NewsCenter

What could go wrong with modifying human DNA?

What is known for sure, is that cutting DNA and/or modifying it one place, can have hundreds of other negative side effects, such as sterility, or birth defects in the next generation, or hidden gene defects which do not show up for many years, possibly generations.