Emerging research shows that 15% to 80% of people with certain medical conditions aren’t generating many antibodies, if any, after receiving a COVID vaccine.
According to NBC News, people taking medications that suppress their immune system, those on medication for inflammatory disorders and those with blood cancers showed a significantly weaker antibody response to the vaccine.
An organ transplant study published in JAMA found 46% of 658 transplant patients did not mount an antibody response after two doses of the Pfizer-BioNTech or Moderna vaccines. Researchers think the lack of reaction is probably a result of taking a class of immunosuppressive drugs, called antimetabolites.
“The overwhelming majority of transplant patients, even after a second dose of the vaccine, appear to have suboptimal protection — if any protection — from the vaccine, which is frightening, disappointing and a bit surprising,” Segev said.COVID Vaccines May Not Work on Millions Who Have Underlying Conditions, Yet CDC Continues to Recommend They Get the Shot • Children’s Health Defense