Natural immunity appears to confer longer lasting and stronger protection against SARS-CoV-2 infection, symptomatic disease and hospitalization from the Delta variant compared to Pfizer-BioNTech’s two-dose vaccine-induced immunity, according to a new Israeli preprint study.
In the largest real-world observational study comparing natural immunity gained through previous SARS-CoV-2 infection to vaccine-induced immunity afforded by the Pfizer mRNA vaccine, people who recovered from COVID were much less likely than never-infected, vaccinated people to get Delta, develop symptoms or be hospitalized.
“It’s a textbook example of how natural immunity is really better than vaccination,” Charlotte Thålin, a physician and immunology researcher at Danderyd Hospital and the Karolinska Institute, told Science. “To my knowledge, it’s the first time [this] has really been shown in the context of COVID-19.”Fully Vaccinated With Pfizer? You’re 6 to 13 Times More Likely to Get Delta Than Someone With Natural Immunity, Study Says • Children’s Health Defense