In a 2017 study published in the journal Neuropsychiatric Diseases and Treatment, Austrian and German researchers found that rhodiola promotes a calm state of mind and helps reduce symptoms of burnout, an “occupational phenomenon” caused by chronic workplace stress.
Rhodiola has several mechanisms of action that can explain these findings. For one, it helps balance amounts of the stress hormone cortisol and increase levels of a stress-resisting protein called Hsp70. It also stimulates serotonin and dopamine activity and boosts the synthesis of adenosine triphosphate, the main source of energy for most cellular processes. In addition, compounds in rhodiola like rosavin and salidroside can help fight oxidative stress and inflammation. (Related: The potential neuroprotective properties of salidroside from Rhodiola rosea.)
The optimal dosage of rhodiola for improving symptoms of stress, fatigue or depression is 400 to 600 mg in a single dose per day. If you’re after its performance-enhancing effects, take 200 to 300 mg of the herb an hour or two before exercise. Add black pepper to rhodiola tea to boost absorption.Rhodiola significantly improves mental health and promotes a calm state of mind – Dr. Eddy Bettermann MD