IgG4-related disease (IgG4RD) means FIBROSIS and organ destruction

There are quite a few pathologies associated with IgG4RD, but they all involve the fibro-inflammatory processes inherent to it. Figure 3 shows an example of one of these manifestations, namely retroperitoneal fibrosis with aorta involvement, from a paper published in 2014 characterizing IgG4-related disease using PET/CT methods.23

I found a paper entitled: “Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease.24 The folks who penned this paper wrote:

IgG4-related systemic disease should be considered in any patient found to have aortitis (or periaortitis).

IgG4-related disease (IgG4RD) means FIBROSIS and organ destruction